Synthetic peptides offer a range of benefits, making peptide therapy quite versatile. The ARA-290 peptide (also called cibinetide) is an ideal option for patients who are interested in enhanced tissue repair, a reduction in chronic inflammation, and more. At Beyond Human in Parker and Aurora, CO, patients regularly come in for treatment with the ARA-290 peptide.
What Is ARA-290?
The ARA-290 peptide was created by Araim Pharmaceuticals. This small synthetic peptide is composed of 11 amino acids. It comes from a glycoprotein hormone called erythropoietin. Erythropoietin (EPO) is produced by the kidneys, bone marrow, spleen, brain, liver, and lungs. It is used to trigger the production of red blood cells (erythropoiesis).
Araim Pharmaceuticals discovered the Innate Repair Receptor (IRR), which interacts with the EPO hormone, resulting in a wide variety of health benefits. Receptors are types of protein molecules in and on cells that bond with substances, causing various physiological responses.
EPO’s interaction with the IRR can also have a negative effect: It can result in overproduction of red blood cells, causing thrombotic complications. Because the ARA-290 peptide is nonhematopoietic, no red blood cell production occurs, avoiding this issue entirely.
The Many Benefits of ARA-290
The ARA-290 peptide offers a variety of benefits, from increased tissue protection to tissue repair to reduction of chronic inflammation and pain. Treatment with ARA-290 is a targeted process, one that could have a lot of potential therapeutic uses in medicine. Research is still being conducted to understand the full extent of its applications.
Increases Tissue Protection
The ARA-290 peptide aids in protecting the tissues of the body. It has been seen to reduce the occurrence of apoptosis (programmed cell death). Additionally, when stressful conditions are present, this peptide increases the likelihood of survival of several types of cells.
ARA-290 increases the chance of survival for neurons, endothelial cells (cells that cover the insides of lymphatic vessels and blood vessels), cardiomyocytes (heart muscle cells), and more. It also helps these cells function in stressful circumstances.
Strengthens the Immune System
ARA-290 improves the immune system. When ARA-290 binds to the tissue-protective receptor (TPR) on immune cells like lymphocytes, macrophages, dendritic cells, and mast cells, their functions are boosted.
This process can bolster the body’s defenses and improve its response. Protection against diseases and infections is increased, the severity of illnesses is reduced, and resilience and overall wellness are enhanced.
Reduces Aging-Associated Changes
ARA-290 can reduce certain changes relating to the aging process. Treatment with ARA-290 can result in significantly less age-associated blood-pressure elevation. It can potentially result in reduced age-related frailty and heart function decline. Additionally, age-related chronic inflammation can be decreased.
Improves Tissue Repair and Regeneration
This synthetic peptide effectively boosts the tissue repair and regeneration process, including angiogenesis (new blood vessel formation). Increased angiogenesis enhances blood flow to injury sites, improving wound healing and healing after surgery. Wound closure is enhanced, the chance of complications is decreased, and the amount of scar tissue that forms is reduced.
ARA-290’s tissue-repair enhancement also improves the body’s ability to repair and regenerate damaged nerves. Nerves can be damaged as a result of trauma and health conditions like diabetes, celiac disease, thyroid illness, and HIV. Damaged nerves cause issues with loss of sensation and chronic pain.
Decreases Chronic Inflammation
The immune system’s natural response to threats results in inflammation, which is a sign that the body is fighting off the threats or healing itself. In some cases, however, inflammation can occur for longer than normal. Inflammation can also occur without threats, affecting healthy tissues.
In these cases, inflammation is considered to be chronic rather than acute. Chronic inflammation accompanies numerous health issues, such as diabetes, heart disease, and various autoimmune conditions.
The ARA-290 peptide helps to modulate the body’s immune response, reducing chronic inflammation. It does this by increasing anti-inflammatory mediator expression and decreasing creation of pro-inflammatory cytokines.
Reduces Pain
Chronic pain is a problem that accompanies several health conditions, including arthritis, multiple sclerosis, ulcers, sarcoidosis, diabetes, and amputation. ARA-290 has been seen to reduce chronic pain related to conditions like these. This is due to its ability to decrease inflammation and repair tissue, including nerve tissue.
Find Out If ARA-290 Is Right for You
At Beyond Human‘s medical clinics in Parker and Aurora, CO, we offer a variety of peptides to meet patients’ health and wellness needs. Get in touch today to schedule a personalized consultation with one of our experts and find out whether ARA-290 is right for you.